Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 15/20 | 0.59 |
| ▸ | NLRP3 | Q96P20 | 10/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26090234 | 1.00 | IL1B (0.59) | IL1BNLRP3KCNH2TNF | |
| SCHEMBL26090244 | 1.00 | IL1B (0.59) | IL1BNLRP3KCNH2TNF | |
| SCHEMBL30374843 | 0.89 | IL1B (0.75) | IL1BNLRP3KCNH2TNF | |
| SCHEMBL26089337 | 0.89 | IL1B (0.75) | IL1BNLRP3KCNH2TNF | |
| SCHEMBL26089348 | 0.89 | IL1B (0.75) | IL1BNLRP3KCNH2TNF | |
| SCHEMBL25296603 | 0.87 | IL1B (0.70) | IL1BNLRP3 | |
| SCHEMBL30375080 | 0.87 | IL1B (0.70) | IL1BNLRP3 | |
| SCHEMBL25296602 | 0.87 | IL1B (0.70) | IL1BNLRP3 | |
| SCHEMBL26090434 | 0.87 | IL1B (0.50) | IL1BNLRP3KCNH2TNF | |
| SCHEMBL26090420 | 0.87 | IL1B (0.50) | IL1BNLRP3KCNH2TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250002470-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | ZHEJIANG AIXPLORER BIOTECH CO., LTD. (CN) | 2025-01-02 | — | — | US | disclosed |
| EP-4421068-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Zhejiang Aixplorer Biotech Co., Ltd. (CN) | 2024-08-28 | — | — | EP | disclosed |
| CN-116102535-A | Nitrogen-containing compound, preparation method and application thereof | 索智生物科技（浙江）有限公司 | 2023-05-12 | — | — | CN | disclosed |
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250002470-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | NOD1, NLRP3, NLRP1 | IL1B 9/4885NLRP3 2/4885KCNH2 2350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.