SCHEMBL30375451

SCHEMBL30375451

Cc1cc(Cc2cc(C)cc(Cc3c(C)ccc(C)c3O)c2O)c(O)c(Cc2c(C)ccc(C)c2O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AMY1A P0DUB6 1/20 0.56
CYP2C9 P11712 3/20 0.50
CYP2C19 P33261 3/20 0.50
HIF1A Q16665 3/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
CYP2D6 P10635 1/20 0.49
HSD17B10 Q99714 1/20 0.49
HSPA5 P11021 1/20 0.47
GAA P10253 3/20 0.33
ALDH1A1 P00352 2/20 0.33
TAAR1 Q96RJ0 1/20 0.33
SELL P14151 1/20 0.33
SELP P16109 1/20 0.33
SELE P16581 1/20 0.33
SHBG P04278 1/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29290543 1.00 AMY1A (0.56) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL22500183 0.91 AMY1A (0.46) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL22534405 0.89 AMY1A (0.50) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29215724 0.83 AMY1A (0.50) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL30375478 0.83 AMY1A (0.50) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL12128513 0.82 AMY1A (0.46) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL7984870 0.81 AMY1A (0.62) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL7749757 0.81 CYP2C19 (0.60) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL20169592 0.81 AMY1A (0.41) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL278350 0.79 ALDH1A1 (0.46) CYP2C9CYP2C19HIF1ASMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113646052-B Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument 百乐墨水株式会社 2024-05-17 CN disclosed
CN-113785023-B Water-based ink composition for reversible thermochromic writing instrument, refill for refill and water-based ballpoint pen incorporating same 株式会社百乐 2023-05-12 CN disclosed