SCHEMBL30375487

SCHEMBL30375487

Cc1cc(C2(c3ccc(O)c(C)c3)CCC(c3ccc(O)cc3)CC2)ccc1O

nearest known ligand 0.59

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 20/20 0.59
ESR1 P03372 12/20 0.59
CYP3A4 P08684 2/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2D6 P10635 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3807813 1.00 ESR2 (0.59) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL4816643 0.91 ESR2 (0.63) ESR2ESR1
SCHEMBL9066299 0.88 ESR2 (0.59) ESR2ESR1
SCHEMBL9849920 0.87 ESR2 (0.61) ESR2ESR1CYP2C9
SCHEMBL3809870 0.86 ESR2 (0.51) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL3192802 0.85 ESR2 (0.54) ESR2ESR1CYP3A4CYP2C9
SCHEMBL30165897 0.83 ESR1 (0.69) ESR2ESR1
SCHEMBL4200651 0.83 ESR1 (0.69) ESR2ESR1
SCHEMBL29393324 0.83 ESR1 (0.69) ESR2ESR1
SCHEMBL2951103 0.82 ESR2 (0.61) ESR2ESR1CYP3A4CYP2C9CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113646052-B Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument 百乐墨水株式会社 2024-05-17 CN disclosed
CN-113785023-B Water-based ink composition for reversible thermochromic writing instrument, refill for refill and water-based ballpoint pen incorporating same 株式会社百乐 2023-05-12 CN disclosed