Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 8/20 | 0.63 |
| ▸ | ESR1 | P03372 | 4/20 | 0.63 |
| ▸ | QDPR | P09417 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3807813 | 0.91 | ESR2 (0.59) | ESR2ESR1 | |
| SCHEMBL30375487 | 0.91 | ESR2 (0.59) | ESR2ESR1 | |
| SCHEMBL9066299 | 0.88 | ESR2 (0.59) | ESR2ESR1ACHETDP1MEN1 | |
| SCHEMBL15372532 | 0.87 | ESR2 (0.51) | ESR2ESR1QDPRACHEACMSD | |
| SCHEMBL29393324 | 0.85 | ESR1 (0.69) | ESR2ESR1ACHETDP1TP53 | |
| SCHEMBL4200651 | 0.85 | ESR1 (0.69) | ESR2ESR1ACHETDP1TP53 | |
| SCHEMBL30165897 | 0.85 | ESR1 (0.69) | ESR2ESR1ACHETDP1TP53 | |
| SCHEMBL5386114 | 0.83 | ESR1 (0.71) | ESR2ESR1ACHETDP1TP53 | |
| SCHEMBL16581350 | 0.82 | ESR1 (0.60) | ESR2ESR1QDPRACHEACMSD | |
| SCHEMBL930211 | 0.81 | QDPR (0.52) | ESR2ESR1QDPRACMSDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7321054-B2 | Method of producing poly(ortho-methylphenol) | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2008-01-22 | — | — | US | disclosed |
| US-20070197832-A1 | METHOD OF PRODUCING POLY(ORTHO-METHYLPHENOL) | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197832-A1 | METHOD OF PRODUCING POLY(ORTHO-METHYLPHENOL) | COMT, HPD, KDM8 | ESR2 1813/4885ESR1 871/4885QDPR 342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.