SCHEMBL30376243

SCHEMBL30376243

CCCn1cc(S(N)(=O)=O)cn1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.49
KMT2A Q03164 1/20 0.44
NAMPT P43490 11/20 0.40
CYP2C9 P11712 4/20 0.39
CYP3A4 P08684 3/20 0.39
CYP2C19 P33261 1/20 0.39
CA2 P00918 3/20 0.38
KIT P10721 1/20 0.37
ALDH1A1 P00352 1/20 0.37
PIK3CD O00329 1/20 0.36
PIP5K1C O60331 1/20 0.36
PIK3CA P42336 1/20 0.36
PIK3CB P42338 1/20 0.36
PI4KA P42356 1/20 0.36
PIK3CG P48736 1/20 0.36
PI4KB Q9UBF8 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17795668 0.85 KMT2A (0.58) KMT2ANAMPTCA2ALDH1A1
SCHEMBL24152939 0.82 L3MBTL1 (0.49) L3MBTL1KMT2ANAMPTCYP2C9CYP3A4
SCHEMBL20757446 0.81 KMT2A (0.38) L3MBTL1KMT2ACA2ALDH1A1PIK3CA
SCHEMBL15690501 0.78 NAMPT (0.50) L3MBTL1KMT2ANAMPTCYP2C9CYP3A4
SCHEMBL626824 0.75 CCNC (0.43) KMT2ANAMPTCA2
SCHEMBL22497185 0.75 FFAR1 (0.46) KMT2ANAMPTCA2PIK3CDPIK3CA
SCHEMBL22497216 0.75 ACHE (0.38) KMT2ACA2ALDH1A1
SCHEMBL22497218 0.75 ACHE (0.38) KMT2ACA2ALDH1A1
SCHEMBL24923656 0.74 KMT2A (0.76) L3MBTL1KMT2AALDH1A1
SCHEMBL23851025 0.74 NAMPT (0.38) KMT2ANAMPTCA2PIK3CDPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116113627-B Ji Yin-dole glucocorticoid receptor antagonists 科赛普特治疗公司 2025-06-03 CN disclosed
CN-116113627-A Ji Yin-indolyl glucocorticoid receptor antagonists 科赛普特治疗公司 2023-05-12 CN disclosed