Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 5/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.34 |
| ▸ | JAK1 | P23458 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 5/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | TYK2 | P29597 | 2/20 | 0.33 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22497216 | 1.00 | ACHE (0.38) | ACHEKMT2AALDH1A1AURKAAURKB | |
| SCHEMBL23851009 | 0.80 | ACHE (0.36) | ACHEKMT2AALDH1A1CA2CA9 | |
| SCHEMBL17795668 | 0.78 | KMT2A (0.58) | KMT2AALDH1A1CA2CA9CA1 | |
| SCHEMBL30376243 | 0.75 | L3MBTL1 (0.49) | KMT2AALDH1A1CA2 | |
| SCHEMBL22497185 | 0.74 | FFAR1 (0.46) | KMT2AAURKAAURKBJAK1CA2 | |
| SCHEMBL15894907 | 0.74 | ACHE (0.42) | ACHEKMT2AALDH1A1JAK1ROCK1 | |
| SCHEMBL1662568 | 0.74 | ACHE (0.42) | ACHEKMT2AALDH1A1JAK1ROCK1 | |
| SCHEMBL1703536 | 0.74 | ACHE (0.42) | ACHEKMT2AALDH1A1JAK1ROCK1 | |
| SCHEMBL30961719 | 0.72 | ACHE (0.53) | ACHEJAK1ROCK1JAK2TYK2 | |
| SCHEMBL30702223 | 0.72 | ACHE (0.53) | ACHEJAK1ROCK1JAK2TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12012392-B2 | Sulfonamide carboxamide compounds | INFLAZOME LIMITED (IE) | 2024-06-18 | — | — | US | disclosed |
| US-20200317637-A1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | INFLAZOME LIMITED (IE) | 2020-10-08 | — | — | US | disclosed |
| CN-111315733-A | Novel sulfonamide carboxamide compounds | 英夫拉索姆有限公司 | 2020-06-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200317637-A1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | NLRP3, NOD1, PYCARD | ACHE 4007/4885KMT2A 2404/4885ALDH1A1 1407/4885 |
| US-12012392-B2 | Sulfonamide carboxamide compounds | NLRP3, PYCARD, NOD1 | ACHE 3501/4885KMT2A 2061/4885ALDH1A1 1293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.