Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.51 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24148772 | 1.00 | HSD11B1 (0.51) | HSD11B1PRKAA2KMT2AGRM5CHRNB2 | |
| SCHEMBL24150078 | 0.95 | HSD11B1 (0.53) | HSD11B1PRKAA2KMT2AGRM5CHRNB2 | |
| SCHEMBL4779 | 0.87 | HSD11B1 (0.52) | HSD11B1PRKAA2KMT2AGRM5SMYD3 | |
| SCHEMBL24151463 | 0.85 | GRM5 (0.53) | HSD11B1PRKAA2GRM5CHRNB2CHRNB4 | |
| SCHEMBL25053099 | 0.85 | HSD11B1 (0.52) | HSD11B1PRKAA2KMT2ACHRNB2CHRNB4 | |
| SCHEMBL24151346 | 0.85 | PRKAA2 (0.55) | HSD11B1PRKAA2ALDH1A1HPGDPRKAA1 | |
| SCHEMBL24150310 | 0.84 | HSD11B1 (0.60) | HSD11B1KMT2AGRM5ALDH1A1HPGD | |
| SCHEMBL24150646 | 0.84 | HTR4 (0.55) | HSD11B1PRKAA2 | |
| SCHEMBL30379651 | 0.84 | HTR4 (0.55) | HSD11B1PRKAA2 | |
| SCHEMBL13267799 | 0.84 | PRKAA2 (0.53) | HSD11B1PRKAA2KMT2ACHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4167982-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV Pharmaceuticals, Inc. (US) | 2023-04-26 | — | — | EP | disclosed |