Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18761926 | 0.83 | POLB (0.65) | POLBNPC1RAB9AKDM4ELMNA | |
| SCHEMBL17080331 | 0.83 | POLB (0.65) | POLBNPC1RAB9AKDM4ELMNA | |
| SCHEMBL30230846 | 0.77 | POLB (0.49) | POLBMAP3K7NPC1RAB9AMAP3K5 | |
| SCHEMBL29828077 | 0.77 | RAB9A (0.57) | POLBNPC1RAB9AKDM4ELMNA | |
| SCHEMBL3377975 | 0.73 | PARP1 (0.51) | HIF1ANPSR1RXFP1SMN1; SMN2PARP1 | |
| SCHEMBL3895087 | 0.73 | POLB (0.50) | POLBNPC1RAB9AKDM4ELMNA | |
| SCHEMBL20448259 | 0.73 | POLB (0.67) | POLBNPC1RAB9AKDM4ELMNA | |
| SCHEMBL29606578 | 0.72 | POLB (0.52) | POLBNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL31121869 | 0.71 | POLB (0.51) | POLBNPC1RAB9AKDM4ELMNA | |
| SCHEMBL15324772 | 0.71 | ALDH1A1 (0.53) | NPC1RAB9AKDM4ELMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4132915-A1 | SUBSTITUTED ISOPHTHALIC ACID DIAMIDES | Bayer Aktiengesellschaft (DE) | 2023-02-15 | — | — | EP | disclosed |