Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3893050 | 0.90 | POLB (0.43) | POLBLMNAKDM4ETDP1HIF1A | |
| SCHEMBL3895100 | 0.82 | POLB (0.47) | POLBLMNAKDM4ETDP1HIF1A | |
| SCHEMBL7258412 | 0.81 | POLB (0.36) | POLBLMNAKDM4ETDP1HIF1A | |
| SCHEMBL17080331 | 0.77 | POLB (0.65) | POLBLMNAKDM4ETDP1HIF1A | |
| SCHEMBL18761926 | 0.77 | POLB (0.65) | POLBLMNAKDM4ETDP1HIF1A | |
| SCHEMBL3896671 | 0.73 | HPGDS (0.49) | POLBLMNAKDM4EMAPTRAB9A | |
| SCHEMBL18779295 | 0.72 | POLB (0.59) | POLBLMNAKDM4ETDP1HIF1A | |
| SCHEMBL31121869 | 0.71 | POLB (0.51) | POLBLMNAKDM4ETDP1MAPT | |
| SCHEMBL12147147 | 0.71 | RAB9A (0.57) | POLBLMNAKDM4ETDP1HIF1A | |
| SCHEMBL3892152 | 0.71 | HPGDS (0.49) | POLBRAB9ANPC1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7511034-B2 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2009-03-31 | — | — | US | claimed |
| US-7229988-B2 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2007-06-12 | — | — | US | claimed |
| US-20060116377-A1 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | OH EU-GENE | 2006-06-01 | — | — | US | claimed |
| US-7229988-B2 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2007-06-12 | — | — | US | disclosed |
| US-20040214827-A1 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SAM-SUNG ELECTRONICS CO., LTD. (KR) | 2004-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116377-A1 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SOD1, DDO, LPO | POLB 2219/4885LMNA 2803/4885KDM4E 3297/4885 |
| US-20040214827-A1 | Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses | SOD1, DDO, LPO | POLB 2348/4885LMNA 2893/4885KDM4E 2974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.