SCHEMBL30382045

SCHEMBL30382045

Cc1ccc(C=C2CC(C(=O)O)CC(=Cc3ccc(N=[N+]=[N-])cc3)C2=O)cc1

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 7/20 0.51
▸ F10 P00742 6/20 0.51
▸ KMT2A Q03164 2/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ CYP1A2 P05177 1/20 0.43
▸ ACHE P22303 2/20 0.41
▸ USP2 O75604 1/20 0.36
▸ STAT3 P40763 1/20 0.36
▸ MAOA P21397 1/20 0.35
▸ MAOB P27338 1/20 0.35
▸ MAPT P10636 3/20 0.35
▸ HTT P42858 2/20 0.35
▸ NPC1 O15118 2/20 0.35
▸ RAB9A P51151 2/20 0.35
▸ HSP90AA1 P07900 1/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ MIF P14174 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30383935 1.00 F2 (0.51) F2F10KMT2AMEN1CYP1A2
SCHEMBL29910947 0.94 F2 (0.56) F2F10CYP1A2STAT3MAPT
SCHEMBL15964849 0.94 F2 (0.56) F2F10CYP1A2STAT3MAPT
SCHEMBL30384724 0.86 USP18 (0.48) F2F10KMT2AMEN1CYP1A2
SCHEMBL26395639 0.85 MAPT (0.50) KMT2AMEN1CYP1A2ACHEUSP2
SCHEMBL17625266 0.82 MAPT (0.46) F2F10KMT2AMEN1CYP1A2
SCHEMBL30383522 0.82 CYP1A2 (0.47) KMT2AMEN1CYP1A2ACHEMAOA
SCHEMBL13870140 0.80 F10 (0.41) F2F10USP2MIF
SCHEMBL28351724 0.80 F2 (0.41) F2F10CYP1A2MAPTHTT
SCHEMBL13886919 0.79 USP18 (0.54) F2F10KMT2AMEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B F2 2/4885F10 22/4885KMT2A 2792/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 F2 5/4885F10 19/4885KMT2A 3188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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