SCHEMBL30384724

SCHEMBL30384724

Cc1ccc(/C=C2\CC(O)C/C(=C\c3ccc(N=[N+]=[N-])cc3)C2=O)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ USP18 Q9UMW8 1/20 0.48
▸ UCHL5 Q9Y5K5 1/20 0.48
▸ KMT2A Q03164 2/20 0.46
▸ CYP1A2 P05177 2/20 0.46
▸ MEN1 O00255 1/20 0.46
▸ ACHE P22303 3/20 0.40
▸ MAOA P21397 1/20 0.37
▸ MAOB P27338 1/20 0.37
▸ NPC1 O15118 2/20 0.37
▸ MAPT P10636 2/20 0.37
▸ RAB9A P51151 2/20 0.37
▸ HSP90AA1 P07900 1/20 0.37
▸ MAPK1 P28482 1/20 0.37
▸ HTT P42858 1/20 0.37
▸ MIF P14174 2/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ DHODH Q02127 1/20 0.35
▸ CYP3A4 P08684 1/20 0.35
▸ CYP2C9 P11712 1/20 0.35
▸ F2 P00734 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13886919 0.93 USP18 (0.54) USP18UCHL5KMT2ACYP1A2MEN1
SCHEMBL26395639 0.88 MAPT (0.50) KMT2ACYP1A2MEN1ACHEMAOA
SCHEMBL30382045 0.86 F2 (0.51) KMT2ACYP1A2MEN1ACHEMAOA
SCHEMBL30383935 0.86 F2 (0.51) KMT2ACYP1A2MEN1ACHEMAOA
SCHEMBL30382557 0.85 USP18 (0.34) USP18UCHL5KMT2ACYP1A2MEN1
SCHEMBL30383522 0.85 CYP1A2 (0.47) KMT2ACYP1A2MEN1ACHEMAOA
SCHEMBL17625266 0.85 MAPT (0.46) KMT2ACYP1A2MEN1ACHEMAOA
SCHEMBL13886925 0.82 MAPT (0.55) USP18UCHL5KMT2ACYP1A2MEN1
SCHEMBL13861280 0.82 MAPT (0.55) USP18UCHL5KMT2ACYP1A2MEN1
SCHEMBL13882616 0.82 MAPT (0.55) USP18UCHL5KMT2ACYP1A2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B USP18 2727/4885UCHL5 2976/4885KMT2A 2792/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 USP18 1916/4885UCHL5 3465/4885KMT2A 3188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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