Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | CTSG | P08311 | 2/20 | 0.33 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.33 |
| ▸ | CMA1 | P23946 | 2/20 | 0.33 |
| ▸ | TACR3 | P29371 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29460862 | 0.69 | NR1I2 (0.37) | NR1I2PRSS1PRSS2PRSS3MAPT | |
| SCHEMBL30438759 | 0.68 | PPARG (0.44) | KDM4EALDH1A1SMN1; SMN2POLBTACR3 | |
| SCHEMBL23823161 | 0.67 | NR1I2 (0.42) | NR1I2PRSS1PRSS2PRSS3 | |
| SCHEMBL22684510 | 0.67 | MCHR1 (0.40) | NR1I2 | |
| SCHEMBL18823613 | 0.66 | HCAR3 (0.50) | MAPT | |
| SCHEMBL29566641 | 0.66 | NR1I2 (0.34) | NR1I2 | |
| SCHEMBL19772965 | 0.65 | NR1I2 (0.37) | KDM4ENR1I2ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL26673673 | 0.65 | NR1I2 (0.40) | KDM4ENR1I2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL29091020 | 0.65 | KDM4E (0.56) | KDM4EALDH1A1SMN1; SMN2TACR3LMNA | |
| SCHEMBL30604151 | 0.65 | KDM4E (0.56) | KDM4EALDH1A1SMN1; SMN2TACR3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116033899-A | Novel compounds as inhibitors of histone deacetylase 6 and pharmaceutical compositions comprising the same | 株式会社 钟根堂 | 2023-04-28 | — | — | CN | disclosed |