SCHEMBL30383487

SCHEMBL30383487

COc1ccc(/C=C/C(=O)c2ccc(O)cc2)cc1COc1cc(C)ccc1C

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 7/20 0.67
▸ KMT2A Q03164 7/20 0.67
▸ LMNA P02545 5/20 0.67
▸ ALDH1A1 P00352 5/20 0.67
▸ KDM4E B2RXH2 2/20 0.67
▸ MAPT P10636 7/20 0.59
▸ SMN1; SMN2 Q16637 3/20 0.59
▸ THRB P10828 1/20 0.59
▸ RECQL P46063 1/20 0.58
▸ CTSL P07711 1/20 0.57
▸ CXCL12 P48061 1/20 0.56
▸ ABCG2 Q9UNQ0 1/20 0.53
▸ CA1 P00915 1/20 0.53
▸ CA2 P00918 1/20 0.53
▸ POLB P06746 2/20 0.52
▸ MAOA P21397 1/20 0.52
▸ MAOB P27338 1/20 0.52
▸ RAB9A P51151 1/20 0.52
▸ L3MBTL1 Q9Y468 1/20 0.52
▸ CAPN1 P07384 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25202171 1.00 MEN1 (0.67) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25209839 0.91 MEN1 (0.66) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL30383181 0.91 MEN1 (0.66) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25217693 0.88 RECQL (0.74) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25198520 0.88 MEN1 (0.62) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL30383445 0.88 MEN1 (0.62) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25195235 0.87 MEN1 (0.82) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25198483 0.87 CYP19A1 (0.64) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25223533 0.86 ALDH1A1 (0.60) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25284637 0.86 ALDH1A1 (0.60) MEN1KMT2ALMNAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed
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