Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.60 |
| ▸ | LMNA | P02545 | 7/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25284637 | 1.00 | ALDH1A1 (0.60) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL25191667 | 0.94 | ALDH1A1 (0.67) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL25200540 | 0.90 | KMT2A (0.70) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL30384262 | 0.90 | KMT2A (0.70) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL25243967 | 0.89 | ALDH1A1 (0.65) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL25196675 | 0.88 | CYP19A1 (0.58) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL25193881 | 0.87 | ALDH1A1 (0.68) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL25202171 | 0.86 | MEN1 (0.67) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL30383487 | 0.86 | MEN1 (0.67) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL25209839 | 0.85 | MEN1 (0.66) | ALDH1A1LMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4429763-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | Yewsavin, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086388-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |