SCHEMBL30383707

SCHEMBL30383707

O=C(/C=C/c1cc(Cl)cc(Cl)c1O)c1ccc(Cl)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.59
▸ MAPK1 P28482 1/20 0.59
▸ BACE1 P56817 1/20 0.55
▸ MAOB P27338 4/20 0.54
▸ CXCL12 P48061 3/20 0.54
▸ CYP1B1 Q16678 1/20 0.51
▸ MEN1 O00255 1/20 0.51
▸ HSP90AA1 P07900 1/20 0.51
▸ KMT2A Q03164 1/20 0.51
▸ LMNA P02545 4/20 0.50
▸ HPGD P15428 2/20 0.50
▸ ATM Q13315 2/20 0.50
▸ SMN1; SMN2 Q16637 2/20 0.50
▸ ERN1 O75460 1/20 0.50
▸ NPC1 O15118 1/20 0.50
▸ CYP1A2 P05177 1/20 0.50
▸ CYP3A4 P08684 1/20 0.50
▸ CYP2D6 P10635 1/20 0.50
▸ CYP2C9 P11712 1/20 0.50
▸ CYP2C19 P33261 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1225026 1.00 MAPT (0.59) MAPTMAPK1BACE1MAOBCXCL12
SCHEMBL1225024 1.00 MAPT (0.59) MAPTMAPK1BACE1MAOBCXCL12
SCHEMBL7171724 0.89 CXCL12 (0.58) MAPTMAPK1BACE1MAOBCXCL12
SCHEMBL7170696 0.89 MAPT (0.56) MAPTMAPK1BACE1MAOBCXCL12
SCHEMBL7171726 0.89 CXCL12 (0.58) MAPTMAPK1BACE1MAOBCXCL12
SCHEMBL7170699 0.89 MAPT (0.56) MAPTMAPK1BACE1MAOBCXCL12
SCHEMBL7658638 0.86 MCL1 (0.64) MAPTMAOBLMNAHPGDATM
SCHEMBL1225557 0.82 LMNA (0.65) MAPTMAPK1MAOBCXCL12CYP1B1
SCHEMBL1225556 0.82 LMNA (0.65) MAPTMAPK1MAOBCXCL12CYP1B1
SCHEMBL7172458 0.82 PTGS2 (0.53) MAPTMAPK1BACE1MAOBCXCL12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAPT 3297/4885MAPK1 3352/4885BACE1 712/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885MAPK1 3412/4885BACE1 1486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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