Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.67 |
| ▸ | CTSB | P07858 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | JAK2 | O60674 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25214895 | 1.00 | CTSL (0.67) | CTSLCTSBMAPTALDH1A1MEN1 | |
| SCHEMBL25212441 | 1.00 | CTSL (0.67) | CTSLCTSBMAPTALDH1A1MEN1 | |
| SCHEMBL25216052 | 0.89 | MAPT (0.67) | CTSLCTSBMAPTALDH1A1MEN1 | |
| SCHEMBL30383996 | 0.89 | MAPT (0.67) | CTSLCTSBMAPTALDH1A1MEN1 | |
| SCHEMBL30383904 | 0.89 | MAPT (0.67) | CTSLCTSBMAPTALDH1A1MEN1 | |
| SCHEMBL25190981 | 0.89 | MAPT (0.67) | CTSLCTSBMAPTALDH1A1MEN1 | |
| SCHEMBL21802489 | 0.82 | CTSL (0.97) | CTSLCTSBMAPTALDH1A1MEN1 | |
| SCHEMBL25203564 | 0.82 | CTSL (0.97) | CTSLCTSBMAPTALDH1A1MEN1 | |
| SCHEMBL31233377 | 0.81 | ALDH1A1 (0.50) | CTSLCTSBMAPTALDH1A1MEN1 | |
| SCHEMBL25219769 | 0.81 | MAPT (0.70) | CTSLCTSBMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233598-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2024-11-14 | — | — | WO | disclosed |
| EP-4429763-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | Yewsavin, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086388-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |