SCHEMBL25212441

SCHEMBL25212441

O=C(C=Cc1ccc(O)c(Cl)c1)c1ccc(N2CCCCC2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CTSL P07711 4/20 0.67
▸ CTSB P07858 4/20 0.67
▸ MAPT P10636 6/20 0.57
▸ ALDH1A1 P00352 3/20 0.57
▸ MEN1 O00255 2/20 0.57
▸ LMNA P02545 2/20 0.57
▸ MAPK1 P28482 2/20 0.57
▸ HTT P42858 2/20 0.57
▸ KMT2A Q03164 2/20 0.57
▸ L3MBTL1 Q9Y468 2/20 0.57
▸ KDM4E B2RXH2 1/20 0.57
▸ JAK2 O60674 1/20 0.57
▸ USP2 O75604 1/20 0.57
▸ POLB P06746 1/20 0.57
▸ GAA P10253 1/20 0.57
▸ THRB P10828 1/20 0.57
▸ HPGD P15428 1/20 0.57
▸ ALOX12 P18054 1/20 0.57
▸ ACHE P22303 1/20 0.56
▸ CXCL12 P48061 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30383849 1.00 CTSL (0.67) CTSLCTSBMAPTALDH1A1MEN1
SCHEMBL25214895 1.00 CTSL (0.67) CTSLCTSBMAPTALDH1A1MEN1
SCHEMBL25216052 0.89 MAPT (0.67) CTSLCTSBMAPTALDH1A1MEN1
SCHEMBL30383996 0.89 MAPT (0.67) CTSLCTSBMAPTALDH1A1MEN1
SCHEMBL30383904 0.89 MAPT (0.67) CTSLCTSBMAPTALDH1A1MEN1
SCHEMBL25190981 0.89 MAPT (0.67) CTSLCTSBMAPTALDH1A1MEN1
SCHEMBL21802489 0.82 CTSL (0.97) CTSLCTSBMAPTALDH1A1MEN1
SCHEMBL25203564 0.82 CTSL (0.97) CTSLCTSBMAPTALDH1A1MEN1
SCHEMBL31233377 0.81 ALDH1A1 (0.50) CTSLCTSBMAPTALDH1A1MEN1
SCHEMBL25219769 0.81 MAPT (0.70) CTSLCTSBMAPTALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B CTSL 357/4885CTSB 51/4885MAPT 3297/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 CTSL 310/4885CTSB 60/4885MAPT 3512/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 CTSL 310/4885CTSB 60/4885MAPT 3512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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