Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 18/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25265259 | 1.00 | ABCB1 (1.00) | ABCB1TSHRCYP2D6HIF1AUSP2 | |
| SCHEMBL25192753 | 1.00 | ABCB1 (1.00) | ABCB1TSHRCYP2D6HIF1AUSP2 | |
| SCHEMBL30382699 | 0.84 | ABCB1 (0.72) | ABCB1LMNAKMT2A | |
| SCHEMBL25201146 | 0.84 | ABCB1 (0.72) | ABCB1LMNAKMT2A | |
| SCHEMBL25188674 | 0.81 | ABCB1 (0.70) | ABCB1TSHRCYP2D6HIF1AALDH1A1 | |
| SCHEMBL6548351 | 0.80 | ABCB1 (0.67) | ABCB1TSHRCYP2D6HIF1AKMT2A | |
| SCHEMBL30382168 | 0.79 | ABCB1 (0.69) | ABCB1TSHRCYP2D6HIF1A | |
| SCHEMBL25209899 | 0.79 | ABCB1 (0.69) | ABCB1TSHRCYP2D6HIF1A | |
| SCHEMBL1330966 | 0.78 | ABCB1 (1.00) | ABCB1 | |
| SCHEMBL25210359 | 0.74 | ABCG2 (0.63) | ABCB1CYP2D6ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4429763-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | Yewsavin, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086388-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |