SCHEMBL25265259

SCHEMBL25265259

O=C(/C=C/c1ccccc1)c1ccccc1OCC(O)CN1CCCCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 18/20 1.00
TSHR P16473 2/20 0.55
CYP2D6 P10635 1/20 0.55
HIF1A Q16665 1/20 0.55
USP2 O75604 1/20 0.53
ALDH1A1 P00352 1/20 0.53
LMNA P02545 1/20 0.53
TP53 P04637 1/20 0.53
GAA P10253 1/20 0.53
THRB P10828 1/20 0.53
ALOX15 P16050 1/20 0.53
HTT P42858 1/20 0.53
KMT2A Q03164 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30384115 1.00 ABCB1 (1.00) ABCB1TSHRCYP2D6HIF1AUSP2
SCHEMBL25192753 1.00 ABCB1 (1.00) ABCB1TSHRCYP2D6HIF1AUSP2
SCHEMBL30382699 0.84 ABCB1 (0.72) ABCB1LMNAKMT2A
SCHEMBL25201146 0.84 ABCB1 (0.72) ABCB1LMNAKMT2A
SCHEMBL25188674 0.81 ABCB1 (0.70) ABCB1TSHRCYP2D6HIF1AALDH1A1
SCHEMBL6548351 0.80 ABCB1 (0.67) ABCB1TSHRCYP2D6HIF1AKMT2A
SCHEMBL30382168 0.79 ABCB1 (0.69) ABCB1TSHRCYP2D6HIF1A
SCHEMBL25209899 0.79 ABCB1 (0.69) ABCB1TSHRCYP2D6HIF1A
SCHEMBL1330966 0.78 ABCB1 (1.00) ABCB1
SCHEMBL25210359 0.74 ABCG2 (0.63) ABCB1CYP2D6ALDH1A1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B ABCB1 1289/4885TSHR 3540/4885CYP2D6 1197/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 ABCB1 3877/4885TSHR 3089/4885CYP2D6 3073/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 ABCB1 3877/4885TSHR 3089/4885CYP2D6 3073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.