SCHEMBL25201146

SCHEMBL25201146

O=C(/C=C/c1ccccc1)c1ccccc1OCC(O)COc1ccccc1C(=O)/C=C/c1ccccc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 2/20 0.72
ABCG2 Q9UNQ0 1/20 0.57
MAPT P10636 4/20 0.54
BCHE P06276 2/20 0.54
CYP2C19 P33261 1/20 0.54
CYSLTR1 Q9Y271 1/20 0.52
MEN1 O00255 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
KMT2A Q03164 1/20 0.50
MAOB P27338 3/20 0.47
PLIN1 O60240 1/20 0.47
LMNA P02545 1/20 0.47
TNFRSF1A P19438 1/20 0.47
ACHE P22303 1/20 0.47
RECQL P46063 1/20 0.47
PLIN5 Q00G26 1/20 0.47
CYP1B1 Q16678 1/20 0.47
ABHD5 Q8WTS1 1/20 0.47
MAOA P21397 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30382699 1.00 ABCB1 (0.72) ABCB1ABCG2MAPTBCHECYP2C19
SCHEMBL25210359 0.88 ABCG2 (0.63) ABCB1ABCG2MAPTBCHECYP2C19
SCHEMBL30383512 0.88 ABCG2 (0.63) ABCB1ABCG2MAPTBCHECYP2C19
SCHEMBL25197971 0.85 ABCG2 (0.60) ABCB1ABCG2MAPTBCHECYP2C19
SCHEMBL25202177 0.84 ABCB1 (0.64) ABCB1MEN1KMT2ALMNAKCNH2
SCHEMBL25193926 0.84 ABCB1 (0.64) ABCB1MEN1KMT2ALMNAKCNH2
SCHEMBL25265259 0.84 ABCB1 (1.00) ABCB1KMT2ALMNA
SCHEMBL25192753 0.84 ABCB1 (1.00) ABCB1KMT2ALMNA
SCHEMBL25283004 0.84 ABCB1 (0.64) ABCB1MEN1KMT2ALMNAKCNH2
SCHEMBL25235490 0.84 ABCB1 (0.64) ABCB1MEN1KMT2ALMNAKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B ABCB1 1289/4885ABCG2 1606/4885MAPT 3297/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 ABCB1 3877/4885ABCG2 3622/4885MAPT 3512/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 ABCB1 3877/4885ABCG2 3622/4885MAPT 3512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.