Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4975349 | 1.00 | SIGMAR1 (0.66) | SIGMAR1MEN1KMT2AALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL11674095 | 0.98 | SIGMAR1 (0.63) | SIGMAR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9866200 | 0.84 | SIGMAR1 (0.66) | SIGMAR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28134518 | 0.84 | SIGMAR1 (0.47) | SIGMAR1MEN1KMT2AALDH1A1BCHE | |
| SCHEMBL9407510 | 0.81 | MEN1 (0.56) | SIGMAR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL2018449 | 0.81 | MEN1 (0.56) | SIGMAR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL16264576 | 0.81 | MEN1 (0.56) | SIGMAR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL18909206 | 0.81 | MEN1 (0.54) | SIGMAR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL29787785 | 0.81 | MEN1 (0.54) | SIGMAR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11096038 | 0.80 | BCHE (0.71) | SIGMAR1MEN1KMT2AALDH1A1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113980032-B | Fused tetracyclic derivative, preparation method thereof and application thereof in medicines | 江苏恒瑞医药股份有限公司 | 2023-06-16 | — | — | CN | disclosed |