Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29011073 | 1.00 | MAPT (0.53) | MAPTLMNACYP1A2THRBALOX15 | |
| SCHEMBL30385875 | 0.88 | KDM4E (0.58) | MAPTLMNACYP1A2THRBALOX15 | |
| SCHEMBL28914531 | 0.88 | KDM4E (0.58) | MAPTLMNACYP1A2THRBALOX15 | |
| SCHEMBL12850681 | 0.88 | LMNA (0.66) | MAPTLMNACYP1A2THRBALOX15 | |
| SCHEMBL28914009 | 0.84 | NPC1 (0.59) | MAPTLMNACYP1A2THRBALOX15 | |
| SCHEMBL30386364 | 0.84 | NPC1 (0.59) | MAPTLMNACYP1A2THRBALOX15 | |
| SCHEMBL12928599 | 0.81 | PIK3CG (0.58) | MAPTLMNACYP1A2THRBALOX15 | |
| SCHEMBL12261 | 0.80 | MAPT (0.61) | MAPTLMNACYP1A2THRBALOX15 | |
| SCHEMBL31119200 | 0.80 | MAPT (0.61) | MAPTLMNACYP1A2THRBALOX15 | |
| SCHEMBL13976992 | 0.80 | PIK3CA (0.46) | MAPTLMNACYP1A2THRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112209894-B | 5-aryl substituted 2-aminobenzoxazole derivative, preparation method and application thereof | 贵州医科大学 | 2023-06-06 | — | — | CN | disclosed |