SCHEMBL12261

SCHEMBL12261

Cc1ccc2oc(N)nc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.61
LMNA P02545 1/20 0.61
CYP1A2 P05177 1/20 0.61
THRB P10828 1/20 0.61
ALOX15 P16050 1/20 0.61
MAPK1 P28482 1/20 0.61
RAB9A P51151 11/20 0.58
NPC1 O15118 10/20 0.58
KDM4E B2RXH2 9/20 0.58
ALDH1A1 P00352 8/20 0.58
SMN1; SMN2 Q16637 7/20 0.58
HPGD P15428 7/20 0.58
HSD17B10 Q99714 6/20 0.58
TP53 P04637 4/20 0.58
NFKB1 P19838 4/20 0.55
NFKB2 Q00653 4/20 0.55
RELA Q04206 4/20 0.55
CASP3 P42574 3/20 0.54
SENP7 Q9BQF6 3/20 0.54
SENP6 Q9GZR1 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31119200 1.00 MAPT (0.61) MAPTLMNACYP1A2THRBALOX15
SCHEMBL30385875 0.85 KDM4E (0.58) MAPTLMNACYP1A2THRBALOX15
SCHEMBL28914531 0.85 KDM4E (0.58) MAPTLMNACYP1A2THRBALOX15
SCHEMBL557792 0.84 PIK3CG (0.61) MAPTLMNACYP1A2THRBALOX15
SCHEMBL29011073 0.80 MAPT (0.53) MAPTLMNACYP1A2THRBALOX15
SCHEMBL30387174 0.80 MAPT (0.53) MAPTLMNACYP1A2THRBALOX15
SCHEMBL29442076 0.79 NPC1 (0.61) MAPTRAB9ANPC1KDM4EALDH1A1
SCHEMBL12850681 0.79 LMNA (0.66) MAPTLMNACYP1A2THRBALOX15
SCHEMBL9105844 0.79 NPC1 (0.61) MAPTRAB9ANPC1KDM4EALDH1A1
SCHEMBL903255 0.79 NPC1 (0.61) MAPTRAB9ANPC1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 266 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026104312-A1 STABLE MOMETASONE FUROATE COMPOSITIONS LTS LOHMANN THERAPIE-SYSTEME AG (DE) 2026-05-21 WO claimed
EP-2922553-B1 TREATMENT OF ALLERGIC RHINITIS USING A COMBINATION OF MOMETASONE AND OLOPATADINE GLENMARK SPECIALTY SA (CH) 2026-05-06 EP claimed
US-12600696-B2 Aromatic compounds Xeniopro GmbH (DE) 2026-04-14 US claimed
EP-3806946-B1 SYSTEMS AND METHODS FOR SINUS ACCESS FIAGON GMBH (DE) 2025-10-15 EP claimed
EP-3713918-B1 SULFASALAZINE SALTS, PRODUCTION PROCESSES AND USES MEDAC GES FUER KLINISCHE SPEZIALPRAEPARATE MBH (DE) 2025-07-23 EP claimed
EP-3943073-B1 BIODEGRADABLE POLYMER MICROPARTICLE CONTAINING STEROID-BASED DRUG AND PREPARATION METHOD THEREFOR REGENBIOTECH INC (KR) 2025-03-26 EP claimed
EP-3755375-B1 TREATMENT OF ALLERGIC RHINITIS IN PEDIATRIC SUBJECTS USING A COMBINATION OF MOMETASONE AND OLOPATADINE GLENMARK SPECIALTY SA (CH) 2025-03-05 EP claimed
EP-3791826-B1 SELF-EXPANDING DEVICES INTERSECT ENT INC (US) 2025-01-29 EP claimed
EP-3866894-B1 PHARMACEUTICAL ADMINISTRATION TO NEONATES, INFANTS AND CHILDREN VECTURA DELIVERY DEVICES LTD (GB) 2025-01-15 EP claimed
EP-3431096-B1 GLUCOCORTICOID COMBINED WITH POLYETHYLENE GLYCOL-MODIFIED INTERLEUKIN-2 FOR TREATING RESPIRATORY DISEASE XIE YANHUI (CN) 2024-12-18 EP claimed
US-RE37781-E1 VIRICIDES, PROTEASE INHIBITOR DUPONT PHARMACEUTICALS COMPANY 2002-07-02 US claimed
US-5811422-A USEFUL FOR TREATING VIRAL INFECTIONS THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1998-09-22 US claimed
EP-0837855-A4 METHOD FOR PREPARING N-MONOSUBSTITUTED AND N,N'-DISUBSTITUTED UNSYMMETRICAL CYCLIC UREAS DU PONT MERCK PHARMA (US) 1998-09-02 EP claimed
EP-0837855-A1 METHOD FOR PREPARING N-MONOSUBSTITUTED AND N,N'-DISUBSTITUTED UNSYMMETRICAL CYCLIC UREAS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1998-04-29 EP claimed
EP-0815108-A1 CYCLIC UREA HIV PROTEASE INHIBITORS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1998-01-07 EP claimed
US-5683999-A Cyclic urea HIV protease inhibitors THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1997-11-04 US claimed
US-5610294-A VIRAL TREATMENT THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1997-03-11 US claimed
WO-1996040652-A1 METHOD FOR PREPARING N-MONOSUBSTITUTED AND N,N'-DISUBSTITUTED UNSYMMETRICAL CYCLIC UREAS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-12-19 WO claimed
WO-1996029329-A1 CYCLIC UREA HIV PROTEASE INHIBITORS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-09-26 WO claimed
US-5532357-A Method for preparing N-monosubstituted and N,N'-disubstituted unsymmetrical cyclic ureas THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1996-07-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600696-B2 Aromatic compounds CCR1, CCRL2, AHR MAPT 4404/4885LMNA 832/4885CYP1A2 724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.