Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.31 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.31 |
| ▸ | SLC16A1 | P53985 | 3/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | MCTS1 | Q9ULC4 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26599351 | 0.91 | P2RX7 (0.34) | P2RX7TRPA1TRPV1DHODHSLC16A3 | |
| SCHEMBL29454971 | 0.91 | P2RX7 (0.34) | P2RX7TRPA1TRPV1DHODHSLC16A3 | |
| SCHEMBL23142280 | 0.91 | MARS1 (0.35) | P2RX7TRPA1TRPV1DHODHSLC16A3 | |
| SCHEMBL15862865 | 0.88 | DHODH (0.36) | TRPA1TRPV1DHODHSLC16A3SLC16A1 | |
| SCHEMBL685550 | 0.84 | SLC2A1 (0.36) | TRPV1DHODHALDH1A1 | |
| SCHEMBL23142315 | 0.83 | P2RX7 (0.36) | P2RX7ALDH1A1 | |
| SCHEMBL13349737 | 0.83 | SLC2A1 (0.36) | DHODH | |
| SCHEMBL30388183 | 0.82 | SCN9A (0.36) | TRPA1TRPV1SCN9AGRM2DHODH | |
| SCHEMBL10075530 | 0.81 | SLC2A1 (0.41) | — | |
| SCHEMBL685536 | 0.81 | SLC2A1 (0.34) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108658816-B | N-aryl amidine substituted trifluoroethyl sulfide derivatives useful as acaricides and insecticides | 拜尔农作物科学股份公司 | 2023-05-02 | — | — | CN | claimed |
| CN-108658816-B | N-aryl amidine substituted trifluoroethyl sulfide derivatives useful as acaricides and insecticides | 拜尔农作物科学股份公司 | 2023-05-02 | — | — | CN | disclosed |