SCHEMBL26599351

SCHEMBL26599351

O=C(Cl)c1cc(Cn2nnnc2C(F)(F)F)nn1-c1ncccc1Cl

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ P2RX7 Q99572 6/20 0.34
▸ TRPA1 O75762 2/20 0.33
▸ TRPV1 Q8NER1 2/20 0.33
▸ DHODH Q02127 1/20 0.32
▸ SLC16A3 O15427 4/20 0.31
▸ SLC16A1 P53985 4/20 0.31
▸ RORC P51449 1/20 0.31
▸ MCTS1 Q9ULC4 2/20 0.31
▸ KDM4E B2RXH2 1/20 0.30
▸ L3MBTL1 Q9Y468 1/20 0.30
▸ MEN1 O00255 1/20 0.30
▸ PPARG P37231 1/20 0.30
▸ KMT2A Q03164 1/20 0.30
▸ NR2E3 Q9Y5X4 1/20 0.30
▸ NCOR2 Q9Y618 1/20 0.30
▸ MALT1 Q9UDY8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29454971 1.00 P2RX7 (0.34) P2RX7TRPA1TRPV1DHODHSLC16A3
SCHEMBL23142280 0.92 MARS1 (0.35) P2RX7TRPA1TRPV1DHODHSLC16A3
SCHEMBL30388796 0.91 P2RX7 (0.33) P2RX7TRPA1TRPV1DHODHSLC16A3
SCHEMBL15862865 0.89 DHODH (0.36) TRPA1TRPV1DHODHSLC16A3SLC16A1
SCHEMBL23142315 0.84 P2RX7 (0.36) P2RX7KDM4EL3MBTL1MEN1KMT2A
SCHEMBL24287198 0.82 TRPA1 (0.34) TRPA1TRPV1DHODHSLC16A3SLC16A1
SCHEMBL385572 0.82 KDM4E (0.44) TRPA1TRPV1SLC16A3SLC16A1KDM4E
SCHEMBL12112877 0.81 KDM4E (0.34) P2RX7TRPA1TRPV1DHODHSLC16A3
SCHEMBL13085032 0.81 NTRK1 (0.34) TRPV1DHODHMALT1
SCHEMBL684736 0.80 NTRK1 (0.33) TRPV1DHODHMALT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12545661-B2 Process for preparing a tetrazole-substituted anthranilic acid diamide derivative BAYER AKTIENGESELLSCHAFT (DE) 2026-02-10 — — US disclosed
US-20230339899-A1 PROCESS FOR PREPARING A TETRAZOLE-SUBSTITUTED ANTHRANILIC ACID DIAMIDE DERIVATIVE BAYER AKTIENGESELLSCHAFT (DE) 2023-10-26 — — US disclosed
CN-116057054-A Process for preparing tetrazole-substituted anthranilic acid diamide derivatives 拜耳公司 2023-05-02 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230339899-A1 PROCESS FOR PREPARING A TETRAZOLE-SUBSTITUTED ANTHRANILIC ACID DIAMIDE DERIVATIVE ALAD, DAO, AASDHPPT P2RX7 1801/4885TRPA1 1960/4885TRPV1 2518/4885
US-12545661-B2 Process for preparing a tetrazole-substituted anthranilic acid diamide derivative ACMSD, ADH1C, ADH1A P2RX7 3439/4885TRPA1 753/4885TRPV1 1216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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