Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 4/20 | 0.60 |
| ▸ | HSPA2 | P54652 | 2/20 | 0.60 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13222393 | 1.00 | HSPA5 (0.60) | HSPA5HSPA2HSPA9RAB9AALDH1A1 | |
| SCHEMBL13222397 | 0.84 | HSPA5 (0.57) | HSPA5HSPA2HSPA9RAB9AALDH1A1 | |
| SCHEMBL30302026 | 0.82 | HSPA5 (0.55) | HSPA5HSPA2HSPA9RAB9AALDH1A1 | |
| SCHEMBL13753488 | 0.81 | RAB9A (0.62) | HSPA5HSPA2HSPA9RAB9AALDH1A1 | |
| SCHEMBL12376694 | 0.81 | RAB9A (0.66) | RAB9AALDH1A1HPGDHDAC1MEN1 | |
| SCHEMBL30302029 | 0.81 | RAB9A (0.55) | HSPA5HSPA2HSPA9RAB9AALDH1A1 | |
| SCHEMBL30302021 | 0.77 | HSPA5 (0.50) | HSPA5HSPA2HSPA9RAB9AALDH1A1 | |
| SCHEMBL8144685 | 0.76 | HSPA5 (0.61) | HSPA5HSPA2HSPA9RAB9AALDH1A1 | |
| SCHEMBL13222414 | 0.76 | RAB9A (0.60) | HSPA5HSPA2HSPA9RAB9AALDH1A1 | |
| SCHEMBL3038390 | 0.76 | RAB9A (0.60) | HSPA5HSPA2HSPA9RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230091297-A1 | INHIBITORS OF HSP70 PROTEINS | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2023-03-23 | — | — | US | disclosed |
| WO-2021183942-A1 | INHIBITORS OF HSP70 PROTEINS | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2021-09-16 | — | — | WO | disclosed |
| US-20100217008-A1 | PROCESS FOR THE PREPARATION OF VALSARTAN AND INTERMEDIATE PRODUCTS | RATIOPHARM GMBH (DE) | 2010-08-26 | — | — | US | disclosed |
| US-20100217008-A1 | PROCESS FOR THE PREPARATION OF VALSARTAN AND INTERMEDIATE PRODUCTS | RATIOPHARM GMBH (DE) | 2010-08-26 | — | — | US | disclosed |
| US-20100217008-A1 | PROCESS FOR THE PREPARATION OF VALSARTAN AND INTERMEDIATE PRODUCTS | RATIOPHARM GMBH (DE) | 2010-08-26 | — | — | US | disclosed |
| EP-2097395-A1 | PROCESS FOR THE PREPARATION OF VALSARTAN AND INTERMEDIATE PRODUCTS | Ratiopharm GmbH (DE) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008071400-A1 | PROCESS FOR THE PREPARATION OF VALSARTAN AND INTERMEDIATE PRODUCTS | RATIOPHARM GMBH (DE) | 2008-06-19 | — | — | WO | disclosed |
| WO-2008071400-A1 | PROCESS FOR THE PREPARATION OF VALSARTAN AND INTERMEDIATE PRODUCTS | RATIOPHARM GMBH (DE) | 2008-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100217008-A1 | PROCESS FOR THE PREPARATION OF VALSARTAN AND INTERMEDIATE PRODUCTS | REN, ACE, AGT | HSPA5 2533/4885HSPA2 4198/4885HSPA9 4236/4885 |
| US-20230091297-A1 | INHIBITORS OF HSP70 PROTEINS | HSPA2, HSP90AB2P, HSP90AB1 | HSPA5 14/4885HSPA2 1/4885HSPA9 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.