Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26101402 | 0.83 | ALDH1A1 (0.45) | KDM4EMAPTGAAALDH1A1POLB | |
| SCHEMBL2442757 | 0.76 | ALDH1A1 (0.52) | KDM4EL3MBTL1NPC1RAB9AKMT2A | |
| SCHEMBL2442756 | 0.76 | ALDH1A1 (0.52) | KDM4EL3MBTL1NPC1RAB9AKMT2A | |
| SCHEMBL22959274 | 0.76 | CA12 (0.49) | KDM4EGAAALDH1A1POLBCYP1A2 | |
| SCHEMBL5781494 | 0.76 | ATM (0.47) | KDM4EKMT2AMAPTGAAALDH1A1 | |
| SCHEMBL2486329 | 0.75 | LMNA (0.45) | KDM4EL3MBTL1ALOX15NPC1RAB9A | |
| SCHEMBL3595923 | 0.75 | KMT2A (0.55) | KDM4EL3MBTL1NPC1RAB9AKMT2A | |
| SCHEMBL3595919 | 0.75 | KMT2A (0.55) | KDM4EL3MBTL1NPC1RAB9AKMT2A | |
| SCHEMBL31079415 | 0.75 | KMT2A (0.55) | KDM4EL3MBTL1NPC1RAB9AKMT2A | |
| SCHEMBL25706410 | 0.75 | KMT2A (0.55) | KDM4EL3MBTL1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4423068-B1 | RXFP1 AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2025-12-03 | — | — | EP | disclosed |
| US-20250011288-A1 | RXFP1 AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2025-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250011288-A1 | RXFP1 AGONISTS | RXFP1, RXFP2, RXFP3 | KDM4E 3691/4885L3MBTL1 3927/4885ALOX15 1080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.