Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 6/20 | 0.58 |
| ▸ | NPY1R | P25929 | 5/20 | 0.58 |
| ▸ | NPY2R | P49146 | 5/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.56 |
| ▸ | IL1RN | P18510 | 1/20 | 0.54 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.54 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.54 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.54 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30669192 | 0.98 | NPY1R (0.57) | NPY4RNPY1RNPY2ROPRM1OPRD1 | |
| SCHEMBL30636161 | 0.95 | NPBWR1 (0.58) | NPY4RNPY1RNPY2RKISS1RNPBWR1 | |
| SCHEMBL29440486 | 0.95 | NPBWR1 (0.58) | NPY4RNPY1RNPY2RKISS1RNPBWR1 | |
| SCHEMBL30259946 | 0.94 | GHSR (0.51) | NPY4RNPY1RNPY2ROPRM1OPRD1 | |
| SCHEMBL29416145 | 0.94 | KISS1R (0.56) | NPY4RNPY1RNPY2ROPRM1OPRD1 | |
| SCHEMBL29577231 | 0.94 | NPY4R (0.62) | NPY4RNPY1RNPY2ROPRM1OPRD1 | |
| SCHEMBL29510997 | 0.94 | NPY1R (0.58) | NPY4RNPY1RNPY2ROPRM1OPRD1 | |
| SCHEMBL29577262 | 0.94 | NPY4R (0.62) | NPY4RNPY1RNPY2ROPRM1OPRD1 | |
| SCHEMBL30272481 | 0.93 | KISS1R (0.57) | NPY4RNPY1RNPY2ROPRD1KISS1R | |
| SCHEMBL31206184 | 0.93 | KISS1R (0.55) | OPRM1OPRD1KISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230137562-A1 | TAU AGGREGATION INHIBITORS | ADRX, INC. | 2023-05-04 | — | — | US | disclosed |