Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | LATS1 | O95835 | 2/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22746305 | 0.88 | ACACB (0.43) | HTTALDH1A1TSHRPKMSMN1; SMN2 | |
| SCHEMBL25497384 | 0.87 | CKS1B (0.47) | HTTALDH1A1TSHRPKMSMN1; SMN2 | |
| SCHEMBL25497351 | 0.83 | NAMPT (0.43) | HTTALDH1A1TSHRPKMSMN1; SMN2 | |
| SCHEMBL26100199 | 0.80 | TPMT (0.35) | PKMSMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL30392217 | 0.79 | NAMPT (0.43) | MAPTTDP1NPSR1LMNAGAA | |
| SCHEMBL26097394 | 0.79 | MTNR1A (0.39) | ALDH1A1MAPTLMNA | |
| SCHEMBL11961188 | 0.78 | CA2 (0.55) | HTTSMN1; SMN2MAPTTDP1NPSR1 | |
| SCHEMBL17976838 | 0.77 | TDP1 (0.54) | HTTALDH1A1TSHRPKMSMN1; SMN2 | |
| SCHEMBL25367309 | 0.77 | NAMPT (0.47) | MAPTTDP1NPSR1GAACA1 | |
| SCHEMBL26328902 | 0.75 | MAPT (0.42) | ALDH1A1SMN1; SMN2MAPTTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4704904-A1 | TETRAZINE-BASED TARGETING AGENTS FOR IN VIVO DELIVERY OF A PAYLOAD | Tambo, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2025059685-A1 | METHODS FOR IN VIVO TARGETED DELIVERY OF A PAYLOAD | TAMBO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| WO-2024229427-A1 | TETRAZINE-BASED TARGETING AGENTS FOR IN VIVO DELIVERY OF A PAYLOAD | TAMBO, INC. (US) | 2024-11-07 | — | — | WO | disclosed |
| EP-4422696-A1 | TETRAZINE CONJUGATES FOR IN VIVO TARGETED DELIVERY OF A PAYLOAD | Tambo, Inc. (US) | 2024-09-04 | — | — | EP | disclosed |
| WO-2023077129-A1 | TETRAZINE CONJUGATES FOR IN VIVO TARGETED DELIVERY OF A PAYLOAD | TAMBO, INC. (US) | 2023-05-04 | — | — | WO | disclosed |