Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.67 |
| ▸ | MAOB | P27338 | 2/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL451456 | 0.94 | MAOA (0.74) | MAOAMAOBSIGMAR1L3MBTL1HTR2A | |
| SCHEMBL6443055 | 0.90 | MAOA (0.70) | MAOAMAOBSIGMAR1L3MBTL1HTR2A | |
| SCHEMBL1226782 | 0.90 | SIGMAR1 (0.71) | MAOAMAOBSIGMAR1L3MBTL1MAPT | |
| SCHEMBL8096690 | 0.90 | SIGMAR1 (0.71) | MAOAMAOBSIGMAR1L3MBTL1MAPT | |
| SCHEMBL676854 | 0.90 | SIGMAR1 (0.71) | MAOAMAOBSIGMAR1L3MBTL1MAPT | |
| SCHEMBL8095284 | 0.90 | SIGMAR1 (0.71) | MAOAMAOBSIGMAR1L3MBTL1MAPT | |
| SCHEMBL8094527 | 0.90 | SIGMAR1 (0.71) | MAOAMAOBSIGMAR1L3MBTL1MAPT | |
| SCHEMBL1433686 | 0.90 | SIGMAR1 (0.71) | MAOAMAOBSIGMAR1L3MBTL1MAPT | |
| SCHEMBL6546948 | 0.90 | SIGMAR1 (0.71) | MAOAMAOBSIGMAR1L3MBTL1MAPT | |
| SCHEMBL8085946 | 0.90 | SIGMAR1 (0.71) | MAOAMAOBSIGMAR1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121574291-A | Borate activated metallocene catalysts | 博里利斯股份公司 | 2026-02-27 | — | — | CN | disclosed |
| EP-3601385-B1 | BORATE-ACTIVATED METALLOCENE CATALYSTS | BOREALIS AG (AT) | 2023-05-03 | — | — | EP | disclosed |