SCHEMBL303932

SCHEMBL303932

CC(C)(C)OC(=O)CNc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.46
PTPRC P08575 2/20 0.46
ALDH1A1 P00352 2/20 0.45
RAB9A P51151 2/20 0.45
MEN1 O00255 1/20 0.45
LMNA P02545 1/20 0.45
MAPT P10636 1/20 0.45
KMT2A Q03164 1/20 0.45
NPC1 O15118 1/20 0.44
HPGD P15428 1/20 0.44
AGTR1 P30556 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
POLB P06746 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA7 P43166 1/20 0.41
CA14 Q9ULX7 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ERCC1 P07992 1/20 0.41
ERCC4 Q92889 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1169286 0.98 PKM (0.45) PKMPTPRCALDH1A1RAB9AMEN1
SCHEMBL25186555 0.95 PKM (0.43) PKMPTPRCALDH1A1RAB9AMEN1
SCHEMBL1688815 0.91 POLB (0.47) PTPRCALDH1A1RAB9AMEN1LMNA
SCHEMBL9080144 0.90 LIPG (0.46) PTPRCALDH1A1RAB9AMEN1LMNA
SCHEMBL5189123 0.85 PTPRC (0.41) PKMPTPRCALDH1A1RAB9AMEN1
SCHEMBL846596 0.85 MAPT (0.44) PTPRCALDH1A1RAB9AMEN1LMNA
SCHEMBL5390150 0.84 MAPT (0.45) PTPRCALDH1A1RAB9AMEN1MAPT
SCHEMBL1039226 0.84 MAPT (0.47) ALDH1A1MEN1MAPTKMT2AAGTR1
SCHEMBL4490577 0.83 AKR1C3 (0.60) ALDH1A1RAB9AMEN1KMT2ANPC1
SCHEMBL9135786 0.83 MAPT (0.52) ALDH1A1RAB9AMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 355 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108431209-A Derived and mature hepatocyte types of liver stem cells and uses thereof 新加坡科技研究局 2018-08-21 CN claimed
CN-122095314-A Photosensitive resin laminate, method for forming resist pattern, and method for manufacturing wiring board having conductor pattern 2026-05-26 CN disclosed
WO-2026100708-A1 PHOTOSENSITIVE RESIN LAMINATE, PHOTOSENSITIVE ELEMENT, AND PATTERN FORMING METHOD 旭化成株式会社 2026-05-15 WO disclosed
CN-114114841-B Photosensitive resin laminate and method for forming resist pattern 旭化成株式会社 2026-05-12 CN disclosed
EP-4689077-A2 CONDITIONALLY IMMORTALIZED STEM CELLS AND USES THEREOF Pluristyx, Inc. (US) 2026-02-11 EP disclosed
US-12371454-B2 Cyclic peptide compound having Kras inhibitory action CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-07-29 US disclosed
WO-2025106912-A1 GAS-BUBBLE BASED DEGRADING LIQUID FOAMS TO DELIVER NUCLEIC ACIDS FRED HUTCHINSON CANCER CENTER (US) 2025-05-22 WO disclosed
WO-2025095102-A1 PHOTOSENSITIVE RESIN LAMINATE, METHOD FOR FORMING RESIST PATTERN, AND METHOD FOR MANUFACTURING WIRING BOARD HAVING CONDUCTOR PATTERN 旭化成株式会社 2025-05-08 WO disclosed
CN-114174922-B Photosensitive resin composition and photosensitive element 旭化成株式会社 2025-03-04 CN disclosed
CN-115524922-B Photosensitive resin composition 旭化成株式会社 2025-02-18 CN disclosed
US-4284779-A Amino acid derivatives E. R. SQUIBB & SONS, INC. (US) 1981-08-18 US disclosed
US-4179434-A Amino acid derivatives E. R. SQUIBB & SONS, INC. (US) 1979-12-18 US disclosed
US-4177277-A INHIBITION OF ANGIOTENSIN-CONVERTING ENZYME E. R. SQUIBB & SONS, INC. (US) 1979-12-04 US disclosed
US-4165320-A Amino acid derivatives E. R. SQUIBB & SONS, INC. (US) 1979-08-21 US disclosed
US-4156786-A Amino acid derivatives E. R. SQUIBB & SONS, INC. (US) 1979-05-29 US disclosed
US-4154946-A Amino mercapto substituted acylamino acids E. R. SQUIBB & SONS, INC. (US) 1979-05-15 US disclosed
US-4154960-A Amino acid derivatives E. R. SQUIBB & SONS, INC. (US) 1979-05-15 US disclosed
US-4146611-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1979-03-27 US disclosed
US-4129571-A Amino acid derivatives E. R. SQUIBB & SONS, INC. (US) 1978-12-12 US disclosed
US-4113715-A Amino acid derivatives E. R. SQUIBB & SONS, INC. (US) 1978-09-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12371454-B2 Cyclic peptide compound having Kras inhibitory action KRAS, NRAS, HRAS PKM 4478/4885PTPRC 1071/4885ALDH1A1 4838/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.