Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30396840 | 0.85 | MEN1 (0.34) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL27620945 | 0.75 | NPC1 (0.41) | KMT2AMEN1L3MBTL1PARP1 | |
| SCHEMBL27620947 | 0.72 | PRMT5 (0.40) | KMT2AMEN1TSHRL3MBTL1PARP1 | |
| SCHEMBL29773951 | 0.72 | GPR119 (0.45) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL27868891 | 0.72 | GPR119 (0.45) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL30974799 | 0.72 | SRC (0.35) | STSKMT2ANR1H2NR1H3PARP1 | |
| SCHEMBL28352935 | 0.72 | PARP1 (0.46) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL28505946 | 0.71 | POLB (0.40) | POLBPARP1 | |
| SCHEMBL4325057 | 0.71 | NR1H2 (0.49) | NR1H2NR1H3PARP1 | |
| SCHEMBL22285173 | 0.71 | NR1H2 (0.49) | NR1H2NR1H3PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115720578-B | And tricyclic derivatives, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-115720578-A | Tricyclic derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-02-28 | — | — | CN | disclosed |