Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27620947 | 0.80 | PRMT5 (0.40) | RAB9AMEN1KMT2AABCB1HDAC1 | |
| SCHEMBL30396299 | 0.75 | STS (0.38) | MEN1KMT2APARP1L3MBTL1 | |
| SCHEMBL2088315 | 0.74 | ACHE (0.52) | NPC1RAB9AMEN1KMT2AHDAC1 | |
| SCHEMBL9259424 | 0.74 | KLK7 (0.48) | MEN1KMT2AABCB1PARP1CTSL | |
| SCHEMBL30968455 | 0.74 | CA1 (0.42) | MEN1KMT2AABCB1PARP1CTSL | |
| SCHEMBL27868891 | 0.73 | GPR119 (0.45) | MEN1KMT2APARP1L3MBTL1 | |
| SCHEMBL29773951 | 0.73 | GPR119 (0.45) | MEN1KMT2APARP1L3MBTL1 | |
| SCHEMBL6500495 | 0.73 | MGLL (0.41) | NPC1RAB9APDE3BPDE3ARORC | |
| SCHEMBL30968489 | 0.73 | CA1 (0.45) | MEN1KMT2ACTSLL3MBTL1RORC | |
| SCHEMBL28352935 | 0.73 | PARP1 (0.46) | MEN1KMT2APARP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101381365-B | Dual action antibiotics | MORPHOCHEM AG KOMB CHEMIE | 2011-07-06 | — | — | CN | disclosed |
| CN-101381365-A | Dual action antibiotics | MORPHOCHEM AG KOMB CHEMIE (DE) | 2009-03-11 | — | — | CN | disclosed |
| CN-1630655-A | Dual action antibiotics | MORPHOCHEM AG FUER KOM (DE) | 2005-06-22 | — | — | CN | disclosed |