Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26466628 | 0.94 | CTSL (0.38) | HDAC4HDAC1HDAC6CTSLCTSB | |
| SCHEMBL30170256 | 0.94 | CTSL (0.38) | HDAC4HDAC1HDAC6CTSLCTSB | |
| SCHEMBL31475423 | 0.93 | HDAC4 (0.41) | HDAC4HDAC1HDAC6CTSLCTSB | |
| SCHEMBL29015510 | 0.88 | HDAC4 (0.39) | HDAC4HDAC1HDAC6CTSLCTSB | |
| SCHEMBL29015511 | 0.88 | HDAC4 (0.39) | HDAC4HDAC1HDAC6CTSLCTSB | |
| SCHEMBL24014373 | 0.84 | CTSL (0.37) | CTSLCTSB | |
| SCHEMBL30396504 | 0.82 | HDAC4 (0.35) | HDAC4HDAC1HDAC6GAACTSS | |
| SCHEMBL24190424 | 0.82 | HDAC4 (0.35) | HDAC4HDAC1HDAC6GAACTSS | |
| SCHEMBL30170007 | 0.82 | CTSL (0.40) | CTSLCTSB | |
| SCHEMBL24189733 | 0.81 | GAA (0.36) | HDAC4HDAC1HDAC6GAACTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4165037-A1 | ANTI-VIRAL COMPOUNDS FOR TREATING CORONAVIRUS, PICORNAVIRUS, AND NOROVIRUS INFECTIONS | Aligos Therapeutics, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |