Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30170256 | 1.00 | CTSL (0.38) | CTSLCTSBHDAC4HDAC1HDAC6 | |
| SCHEMBL31475423 | 0.96 | HDAC4 (0.41) | CTSLCTSBHDAC4HDAC1HDAC6 | |
| SCHEMBL30396703 | 0.94 | HDAC4 (0.37) | CTSLCTSBHDAC4HDAC1HDAC6 | |
| SCHEMBL24014373 | 0.90 | CTSL (0.37) | CTSLCTSB | |
| SCHEMBL30170007 | 0.88 | CTSL (0.40) | CTSLCTSB | |
| SCHEMBL31475427 | 0.84 | HDAC4 (0.44) | HDAC4HDAC1HDAC6 | |
| SCHEMBL24784865 | 0.84 | CTSL (0.36) | CTSLCTSB | |
| SCHEMBL30396504 | 0.84 | HDAC4 (0.35) | HDAC4HDAC1HDAC6 | |
| SCHEMBL24190424 | 0.84 | HDAC4 (0.35) | HDAC4HDAC1HDAC6 | |
| SCHEMBL24189733 | 0.83 | GAA (0.36) | HDAC4HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018126-A1 | ANTI-VIRAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-01-18 | — | — | US | disclosed |
| US-20230140238-A1 | ANTI-VIRAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230140238-A1 | ANTI-VIRAL COMPOUNDS | EIF2AK2, ZC3HAV1, HAVCR2 | CTSL 1088/4885CTSB 829/4885HDAC4 223/4885 |
| US-20240018126-A1 | ANTI-VIRAL COMPOUNDS | EIF2AK2, ZC3HAV1, HAVCR2 | CTSL 1088/4885CTSB 829/4885HDAC4 223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.