SCHEMBL31475423

SCHEMBL31475423

CC(=O)OC(C(=O)NC1CCCC1)[C@H](C[C@@H]1CCNC1=O)NC(=O)OC(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
CTSL P07711 2/20 0.37
CTSB P07858 2/20 0.37
EPHX1 P07099 1/20 0.36
CTSS P25774 1/20 0.36
CTSK P43235 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26466628 0.96 CTSL (0.38) HDAC4HDAC1HDAC6CTSLCTSB
SCHEMBL30170256 0.96 CTSL (0.38) HDAC4HDAC1HDAC6CTSLCTSB
SCHEMBL30396703 0.93 HDAC4 (0.37) HDAC4HDAC1HDAC6CTSLCTSB
SCHEMBL24014373 0.88 CTSL (0.37) CTSLCTSB
SCHEMBL31475427 0.88 HDAC4 (0.44) HDAC4HDAC1HDAC6EPHX1
SCHEMBL30170007 0.84 CTSL (0.40) CTSLCTSB
SCHEMBL25284440 0.81 CTSL (0.50) CTSLCTSBCTSSCTSK
SCHEMBL25243264 0.81 CTSL (0.50) CTSLCTSBCTSSCTSK
SCHEMBL25284441 0.81 CTSL (0.50) CTSLCTSBCTSSCTSK
SCHEMBL24190271 0.81 CAPN1 (0.35) CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025071482-A1 3CPRO INHIBITORS AND METHODS THEREOF AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (A*STAR) (SG) 2025-04-03 WO disclosed