Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RHEB | Q15382 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | ULK1 | O75385 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7873743 | 0.89 | GABRA1 (0.51) | FLT3SRD5A2ALDH1A1HSD17B10HPGD | |
| SCHEMBL7168633 | 0.87 | SRD5A2 (0.56) | FLT3SRD5A2ALDH1A1HSD17B10HPGD | |
| SCHEMBL30396518 | 0.86 | SRD5A2 (0.52) | FLT3SRD5A2ALDH1A1HSD17B10HPGD | |
| SCHEMBL28589083 | 0.84 | FLT3 (0.45) | FLT3SRD5A2ALDH1A1HSD17B10HPGD | |
| SCHEMBL28593849 | 0.83 | SRD5A2 (0.49) | FLT3SRD5A2ALDH1A1HSD17B10HPGD | |
| SCHEMBL20536129 | 0.83 | XDH (0.60) | FLT3ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL30395343 | 0.83 | XDH (0.60) | FLT3ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL28593832 | 0.82 | ULK1 (0.69) | FLT3SRD5A2ALDH1A1HSD17B10HPGD | |
| SCHEMBL7194638 | 0.81 | SRD5A2 (0.55) | FLT3SRD5A2ALDH1A1HSD17B10HPGD | |
| SCHEMBL19331121 | 0.80 | ULK1 (0.53) | FLT3ALDH1A1HSD17B10HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096714-A | Antiviral compounds for the treatment of coronavirus, picornavirus and norovirus infections | 安力高医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| EP-4165037-A1 | ANTI-VIRAL COMPOUNDS FOR TREATING CORONAVIRUS, PICORNAVIRUS, AND NOROVIRUS INFECTIONS | Aligos Therapeutics, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |