Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.35 |
| ▸ | MPL | P40238 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30234869 | 1.00 | TSHR (0.43) | TSHRPOLBGLAGAAPDK2 | |
| SCHEMBL9367414 | 0.84 | GAA (0.40) | TSHRPOLBGLAGAAPDE2A | |
| SCHEMBL29118749 | 0.84 | SCN9A (0.43) | TSHRALOX5APFEN1SCN9AMAPK1 | |
| SCHEMBL22607085 | 0.83 | TSHR (0.45) | TSHRPOLBGLAGAAPDK2 | |
| SCHEMBL714264 | 0.83 | TSHR (0.48) | TSHRPOLBGLAGAAPDK2 | |
| SCHEMBL398001 | 0.83 | ALDH1A1 (0.44) | TSHRPOLBGLAGAAPDE2A | |
| SCHEMBL5502229 | 0.83 | ALDH1A1 (0.44) | TSHRPOLBGLAGAAPDE2A | |
| SCHEMBL30397188 | 0.83 | ALDH1A1 (0.44) | TSHRPOLBGLAGAAPDE2A | |
| SCHEMBL945792 | 0.81 | GAA (0.57) | TSHRPOLBGLAGAAPDE2A | |
| SCHEMBL7779423 | 0.81 | EPHX2 (0.50) | TSHRPOLBGLAGAAPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995004305-A1 | PHOTOSENSITIVE FLUORINATED POLY(AMIC ACID) AMINOACRYLATE SALT | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-02-09 | — | — | WO | disclosed |