Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 6/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30397943 | 1.00 | MAPK13 (0.41) | MAPK13GRM2BTKADORA2A | |
| SCHEMBL30397944 | 0.82 | MAPK13 (0.41) | MAPK13GRM2 | |
| SCHEMBL25526353 | 0.80 | GRM2 (0.43) | MAPK13GRM2 | |
| SCHEMBL25523929 | 0.80 | GRM2 (0.40) | MAPK13GRM2ADORA2A | |
| SCHEMBL30397394 | 0.77 | GRM2 (0.37) | MAPK13GRM2ADORA2A | |
| SCHEMBL25522679 | 0.77 | GRM2 (0.40) | MAPK13GRM2BTK | |
| SCHEMBL25521381 | 0.77 | GRM2 (0.40) | MAPK13GRM2 | |
| SCHEMBL30396233 | 0.77 | GRM2 (0.38) | MAPK13GRM2 | |
| SCHEMBL30397938 | 0.77 | MAPK13 (0.42) | MAPK13GRM2BTK | |
| SCHEMBL30398306 | 0.77 | GRM2 (0.38) | MAPK13GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091726-A1 | INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) | SYROS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |