SCHEMBL303979

SCHEMBL303979

CC(=O)O[Si](CCCCCC[Si](OC(C)=O)(OC(C)=O)OC(C)=O)(OC(C)=O)OC(C)=O

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.40
MAPK1 P28482 1/20 0.40
HIF1A Q16665 1/20 0.40
PAOX Q6QHF9 2/20 0.33
ADRA1A P35348 1/20 0.32
ALDH1A1 P00352 4/20 0.32
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TSHR P16473 1/20 0.32
FAAH O00519 1/20 0.31
NPSR1 Q6W5P4 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL703686 0.97 KDM4E (0.36) KDM4EMAPK1HIF1APAOXALDH1A1
SCHEMBL704685 0.92 KDM4E (0.36) KDM4EMAPK1HIF1APAOXALDH1A1
SCHEMBL7058668 0.91 FAAH (0.43) ALDH1A1LMNAHSD17B10TSHRFAAH
SCHEMBL3237379 0.91 FAAH (0.43) ALDH1A1LMNAHSD17B10TSHRFAAH
SCHEMBL27959383 0.91 FAAH (0.43) ALDH1A1LMNAHSD17B10TSHRFAAH
SCHEMBL1041201 0.91 FAAH (0.43) ALDH1A1LMNAHSD17B10TSHRFAAH
SCHEMBL7058616 0.91 FAAH (0.43) ALDH1A1LMNAHSD17B10TSHRFAAH
SCHEMBL6324952 0.91 FAAH (0.43) ALDH1A1LMNAHSD17B10TSHRFAAH
SCHEMBL7775373 0.91 FAAH (0.43) ALDH1A1LMNAHSD17B10TSHRFAAH
SCHEMBL3793805 0.91 FAAH (0.43) ALDH1A1LMNAHSD17B10TSHRFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8093588-B2 Siloxane-polymer dielectric compositions and related organic field-effect transistors NORTHWESTERN UNIVERSITY (US) 2012-01-10 US claimed
US-20100019237-A1 Siloxane-Polymer Dielectric Compositions and Related Organic Field-Effect Transistors USA AS REPRESENTED BY THE ADMINISTRATOR OF THE NASA 2010-01-28 US claimed
US-8274075-B2 Crosslinked polymeric dielectric materials and electronic devices incorporating same NORTHWESTERN UNIVERSITY (US) 2012-09-25 US disclosed
US-8093588-B2 Siloxane-polymer dielectric compositions and related organic field-effect transistors NORTHWESTERN UNIVERSITY (US) 2012-01-10 US disclosed
US-20110024729-A1 Crosslinked Polymeric Dielectric Materials And Electronic Devices Incorporating Same POLYERA CORPORATION 2011-02-03 US disclosed
US-20100019237-A1 Siloxane-Polymer Dielectric Compositions and Related Organic Field-Effect Transistors USA AS REPRESENTED BY THE ADMINISTRATOR OF THE NASA 2010-01-28 US disclosed
US-7605394-B2 crosslinking reaction product of polyvinyl alcohol, vinyl alcohol-styrene copolymer with hexachlorosiloxane, 1,6-bis(trichlorosilyl)hexane, spin coating the product onto freshly oxygen plasma-treated doped silicon subtrate containing indium tin oxide layer, curing NORTHWESTERN UNIVERSITY (US) 2009-10-20 US disclosed
US-20080161464-A1 Crosslinked polymeric dielectric materials and methods of manufacturing and use thereof USA AS REPRESENTED BY THE ADMINISTRATOR OF THE NASA 2008-07-03 US disclosed
US-20080161464-A1 Crosslinked polymeric dielectric materials and methods of manufacturing and use thereof USA AS REPRESENTED BY THE ADMINISTRATOR OF THE NASA 2008-07-03 US disclosed
WO-2008002660-A9 CROSSLINKED POLYMERIC DIELECTRIC MATERIALS AND METHODS OF MANUFACTURING AND USE THEREOF UNIV NORTHWESTERN (US) 2008-05-08 WO disclosed
WO-2008002660-A2 CROSSLINKED POLYMERIC DIELECTRIC MATERIALS AND METHODS OF MANUFACTURING AND USE THEREOF NORTHWESTERN UNIVERSITY (US) 2008-01-03 WO disclosed