Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | CCNK | O75909 | 1/20 | 0.42 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 15/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.41 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30397528 | 0.85 | PTGDR2 (0.39) | PTGDR2CCNKCDK12HCRTR1HCRTR2 | |
| SCHEMBL25228876 | 0.85 | PTGDR2 (0.39) | PTGDR2CCNKCDK12HCRTR1HCRTR2 | |
| SCHEMBL30397591 | 0.79 | HCRTR1 (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL25226608 | 0.79 | HCRTR1 (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL27233778 | 0.79 | CDK12 (0.56) | PTGDR2CCNKCDK12HCRTR1TIPARP | |
| SCHEMBL27233705 | 0.79 | CDK12 (0.56) | PTGDR2CCNKCDK12HCRTR1TIPARP | |
| SCHEMBL27233710 | 0.79 | CDK12 (0.56) | PTGDR2CCNKCDK12HCRTR1TIPARP | |
| SCHEMBL26120478 | 0.78 | CCNK (0.47) | PTGDR2CCNKCDK12HCRTR1HCRTR2 | |
| Trifluoroacetic Acid SCHEMBL25223128 | 0.72 | HCRTR1 (0.39) | PTGDR2CCNKCDK12HCRTR1HCRTR2 | |
| Trifluoroacetic Acid SCHEMBL30397876 | 0.72 | HCRTR1 (0.39) | PTGDR2CCNKCDK12HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091726-A1 | INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) | SYROS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |