Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 11/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15935271 | 0.79 | CDC7 (0.33) | GRM4MAPK1CDK1GSK3AGSK3B | |
| SCHEMBL19801401 | 0.72 | GRM4 (0.33) | GRM4MAPK1 | |
| SCHEMBL30328027 | 0.72 | GRM4 (0.31) | GRM4 | |
| SCHEMBL30316980 | 0.71 | MAPK1 (0.35) | GRM4MAPK1 | |
| SCHEMBL31303192 | 0.71 | GRM4 (0.45) | GRM4CYP1A2CYP2C19 | |
| SCHEMBL1496225 | 0.71 | GRM4 (0.45) | GRM4CYP1A2CYP2C19 | |
| SCHEMBL6358084 | 0.70 | MAPK1 (0.38) | GRM4MAPK1 | |
| SCHEMBL2675367 | 0.68 | GRM4 (0.33) | GRM4GSK3AGSK3BCYP1A2CYP2C19 | |
| SCHEMBL2693973 | 0.68 | LRRK2 (0.38) | GRM4CDK1GSK3AGSK3BCYP1A2 | |
| SCHEMBL2675127 | 0.68 | GRM4 (0.31) | GRM4CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109789146-B | Chemokine receptor modulators and uses thereof | 拉普特医疗公司 | 2023-04-18 | — | — | CN | disclosed |