Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6358084 | 0.75 | MAPK1 (0.38) | MAPK1GRM4 | |
| SCHEMBL19801401 | 0.73 | GRM4 (0.33) | MAPK1GRM4 | |
| SCHEMBL30876173 | 0.71 | MAPK1 (0.35) | MAPK1 | |
| SCHEMBL3950985 | 0.71 | PDPK1 (0.38) | MAPK1GRM4 | |
| SCHEMBL30180924 | 0.71 | DYRK1A (0.38) | MAPK1 | |
| SCHEMBL14763598 | 0.71 | DYRK1A (0.38) | MAPK1 | |
| SCHEMBL14906033 | 0.71 | MAPK1 (0.45) | MAPK1 | |
| SCHEMBL30398918 | 0.71 | GRM4 (0.37) | MAPK1GRM4 | |
| SCHEMBL30316949 | 0.69 | GRM4 (0.31) | GRM4 | |
| SCHEMBL19258970 | 0.68 | YTHDC1 (0.40) | MAPK1GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4363423-A1 | CDK2 INHIBITORS | Blueprint Medicines Corporation (US) | 2024-05-08 | — | — | EP | disclosed |
| WO-2023278326-A1 | CDK2 INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2023-01-05 | — | — | WO | disclosed |