Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | PNP | P00491 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | VCP | P55072 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1964956 | 0.84 | TK1 (0.46) | TK1BLMPNPUSP2TSHR | |
| SCHEMBL28260991 | 0.78 | TK1 (0.44) | TK1BLMPNPUSP2TSHR | |
| SCHEMBL20673261 | 0.78 | XDH (0.44) | TK1BLMPNPUSP2TSHR | |
| SCHEMBL28484305 | 0.78 | TK1 (0.45) | TK1BLMPNPUSP2TSHR | |
| SCHEMBL30787874 | 0.78 | BLM (0.39) | TK1BLMPNPUSP2TSHR | |
| SCHEMBL237755 | 0.78 | HPGD (0.46) | TK1BLMPNPUSP2TSHR | |
| SCHEMBL23171491 | 0.77 | ADORA3 (0.44) | TK1BLMPNPUSP2TSHR | |
| SCHEMBL14066667 | 0.77 | DNMT1 (0.39) | BLMHBBALDH1A1LMNANFKB1 | |
| SCHEMBL28160273 | 0.77 | HPRT1 (0.43) | TK1PNPADORA3HPRT1 | |
| SCHEMBL19888521 | 0.76 | TK1 (0.46) | TK1BLMPNPUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025038853-A1 | USHER SYNDROME-RELATED GENE MODIFICATION | AMBER BIO INC. (US) | 2025-02-20 | — | — | WO | disclosed |
| US-20240409920-A1 | RNA-GUIDED TRANS-SPLICING OF RNA | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2024-12-12 | — | — | US | disclosed |
| EP-4416290-A1 | RNA-GUIDED TRANS-SPLICING OF RNA | The Broad Institute, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2023064895-A1 | RNA-GUIDED TRANS-SPLICING OF RNA | THE BROAD INSTITUTE, INC. (US) | 2023-04-20 | — | — | WO | disclosed |