Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | ACACA | Q13085 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25372907 | 1.00 | DHFR (0.50) | DHFRKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL25374933 | 0.88 | KMO (0.42) | DHFRKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL30401294 | 0.88 | KMO (0.42) | DHFRKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL509108 | 0.84 | ACACA (0.51) | DHFRKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL25377685 | 0.83 | SYK (0.54) | DHFRKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL30402644 | 0.83 | SYK (0.54) | DHFRKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL509771 | 0.80 | KDM4E (0.52) | DHFRKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL25377291 | 0.79 | PIK3CA (0.46) | MAPT | |
| SCHEMBL30402496 | 0.79 | PIK3CA (0.46) | MAPT | |
| SCHEMBL15068737 | 0.77 | KDM4E (0.42) | KDM4EALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096718-A | Aryl amide compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |