Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 2/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24399702 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1GAAGLAPSMD14 | |
| SCHEMBL15762663 | 0.83 | PSMD14 (0.48) | KDM4EALDH1A1GAAGLAPSMD14 | |
| SCHEMBL14574794 | 0.80 | NAPRT (0.46) | KDM4EALDH1A1PSMD14MAPTHPGD | |
| SCHEMBL18224721 | 0.75 | KDM4E (0.54) | KDM4EALDH1A1GAAGLAPSMD14 | |
| SCHEMBL3553958 | 0.73 | KDM4E (0.53) | KDM4EALDH1A1GAAGLAPSMD14 | |
| SCHEMBL21749959 | 0.73 | KDM4E (0.53) | KDM4EALDH1A1GAAGLAPSMD14 | |
| SCHEMBL31032953 | 0.72 | KDM4E (0.51) | KDM4EALDH1A1GAAGLAPSMD14 | |
| SCHEMBL3630664 | 0.72 | GAA (0.51) | KDM4EALDH1A1GAAGLAPSMD14 | |
| SCHEMBL69886 | 0.71 | PSMD14 (0.73) | KDM4EALDH1A1GAAGLAPSMD14 | |
| SCHEMBL2370623 | 0.71 | KDM4E (0.55) | KDM4EALDH1A1GAAGLAPSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096718-A | Aryl amide compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |