Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ARNT | P27540 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25376925 | 1.00 | ALDH1A1 (0.36) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| SCHEMBL25372994 | 0.89 | TSHR (0.42) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| SCHEMBL25375716 | 0.84 | TSHR (0.42) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| SCHEMBL25376705 | 0.81 | MPO (0.40) | TDP1MEN1KMT2AMPOLMNA | |
| SCHEMBL30401932 | 0.81 | MPO (0.40) | TDP1MEN1KMT2AMPOLMNA | |
| SCHEMBL25377855 | 0.80 | S1PR4 (0.38) | ALDH1A1TSHRKMT2ALMNAPOLB | |
| SCHEMBL30401021 | 0.79 | AR (0.43) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| SCHEMBL25373892 | 0.79 | AR (0.43) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| SCHEMBL25376248 | 0.78 | CSNK2A2 (0.40) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| SCHEMBL30402574 | 0.78 | CSNK2A2 (0.40) | ALDH1A1TSHRTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096718-A | Aryl amide compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |