Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | IGF1R | P08069 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25376248 | 1.00 | CSNK2A2 (0.40) | CSNK2A2CSNK2BLMNAEGFRIGF1R | |
| SCHEMBL25373797 | 0.86 | ALDH1A1 (0.41) | LMNAALDH1A1TSHRTDP1KMT2A | |
| SCHEMBL30402455 | 0.84 | GPR52 (0.39) | MAPTCYP1A2CYP2C9CYP2C19RPS6KB1 | |
| SCHEMBL25374145 | 0.84 | GPR52 (0.39) | MAPTCYP1A2CYP2C9CYP2C19RPS6KB1 | |
| SCHEMBL25377855 | 0.80 | S1PR4 (0.38) | LMNAALDH1A1TSHRKMT2AMAPT | |
| SCHEMBL30401336 | 0.80 | CSNK2A2 (0.41) | CSNK2A2CSNK2BLMNAEGFRIGF1R | |
| SCHEMBL25374531 | 0.80 | CSNK2A2 (0.41) | CSNK2A2CSNK2BLMNAEGFRIGF1R | |
| SCHEMBL25372994 | 0.79 | TSHR (0.42) | LMNAALDH1A1TSHRTDP1KMT2A | |
| SCHEMBL25375892 | 0.79 | ALDH1A1 (0.41) | LMNAALDH1A1TSHRTDP1KMT2A | |
| SCHEMBL24399705 | 0.79 | CSNK2A2 (0.40) | CSNK2A2CSNK2BLMNAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096718-A | Aryl amide compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |