Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 5/20 | 0.38 |
| ▸ | KDR | P35968 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | MDM4 | O15151 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24399590 | 1.00 | FLT1 (0.38) | FLT1KDRLMNAGAAGFER | |
| SCHEMBL24399752 | 0.86 | PARP1 (0.36) | LMNANOS3NOS2ALDH1A1PDE3B | |
| SCHEMBL30402388 | 0.86 | PARP1 (0.36) | LMNANOS3NOS2ALDH1A1PDE3B | |
| SCHEMBL30401336 | 0.84 | CSNK2A2 (0.41) | FLT1KDRLMNAGAA | |
| SCHEMBL25374531 | 0.84 | CSNK2A2 (0.41) | FLT1KDRLMNAGAA | |
| SCHEMBL25379029 | 0.83 | PDE10A (0.53) | KDRLMNAALDH1A1POLBPDE3B | |
| SCHEMBL30401708 | 0.82 | MBOAT4 (0.39) | GAANOS3NOS2ALDH1A1 | |
| SCHEMBL25375372 | 0.82 | MBOAT4 (0.39) | GAANOS3NOS2ALDH1A1 | |
| SCHEMBL24399680 | 0.79 | ALDH1A1 (0.38) | FLT1KDRGAAALDH1A1POLB | |
| SCHEMBL30401923 | 0.79 | ALDH1A1 (0.38) | FLT1KDRGAAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096718-A | Aryl amide compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |