Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 2/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25374531 | 1.00 | CSNK2A2 (0.41) | CSNK2A2CSNK2BSRCBACE1MPO | |
| SCHEMBL24399590 | 0.84 | FLT1 (0.38) | FLT1KDRLMNAGAA | |
| SCHEMBL30402640 | 0.84 | FLT1 (0.38) | FLT1KDRLMNAGAA | |
| SCHEMBL24399705 | 0.84 | CSNK2A2 (0.40) | CSNK2A2CSNK2BSRCTAAR1FLT1 | |
| SCHEMBL30402694 | 0.81 | ROCK1 (0.45) | MPOTAAR1EGFR | |
| SCHEMBL24399633 | 0.81 | ROCK1 (0.45) | MPOTAAR1EGFR | |
| SCHEMBL30402574 | 0.80 | CSNK2A2 (0.40) | CSNK2A2CSNK2BKDM4ELMNAGAA | |
| SCHEMBL25376248 | 0.80 | CSNK2A2 (0.40) | CSNK2A2CSNK2BKDM4ELMNAGAA | |
| SCHEMBL24399680 | 0.78 | ALDH1A1 (0.38) | MPOFLT1KDRGAAHTT | |
| SCHEMBL30401923 | 0.78 | ALDH1A1 (0.38) | MPOFLT1KDRGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096718-A | Aryl amide compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |